:root{
    --brand:#04b39a;
    --brand-600:#039b86; --brand-700:#02806f;
    --ink:#0f172a; --muted:#475569; --bg:#f7faf9; --card:#ffffff; --outline:#e6f4f0;
    --shadow:0 10px 25px rgba(4,179,154,.12), 0 2px 8px rgba(15,23,42,.06);
    --pref:#0ea5e9; --alt:#f97316; --second:#a855f7; --addon:#10b981; --ref:#6b7280;
  }
  *{box-sizing:border-box}
  html,body{margin:0;background:var(--bg);color:var(--ink);font-family:system-ui,-apple-system,Segoe UI,Roboto,Arial;line-height:1.5}
  header{top:0;background:linear-gradient(180deg,#e9fbf7 0%,#f7faf9 70%);border-bottom:1px solid var(--outline);z-index:2}

  .brand{display:flex;align-items:center;gap:14px}
  .brand .logo{width:40px;height:40px;border-radius:12px;background:var(--brand);box-shadow:var(--shadow)}
  h1{font-size:1.35rem;margin:0}
  .sub{color:var(--muted);margin-top:4px}
  .card{background:var(--card);border:1px solid var(--outline);border-radius:14px;padding:16px;margin:16px 0;box-shadow:var(--shadow)}
  .grid{display:grid;grid-template-columns:repeat(12,1fr);gap:12px}
  .col-12{grid-column:span 12}
  .col-4{grid-column:span 12}
  @media(min-width:900px){.col-4{grid-column:span 4}}
  label{display:block;font-size:.9rem;color:var(--muted);margin-bottom:6px}
  input[type="number"], input[type="text"], select{width:100%;padding:10px 12px;border:1px solid var(--outline);border-radius:10px;background:#fff;font-size:1rem}
  input[type="number"]{appearance:textfield}
  input[type="number"]::-webkit-outer-spin-button,input[type="number"]::-webkit-inner-spin-button{appearance:none;margin:0}
  .hint{font-size:.84rem;color:var(--muted)}
  .pill{display:inline-flex;gap:8px;align-items:center;padding:8px 10px;border-radius:999px;background:#eaf8f5;border:1px solid var(--outline);font-size:.85rem}
  .btn{display:inline-flex;align-items:center;justify-content:center;gap:8px;padding:10px 14px;border-radius:12px;border:1px solid var(--brand);background:var(--brand);color:#fff;font-weight:600;cursor:pointer}
  .btn.secondary{background:#fff;color:var(--brand);border-color:var(--brand)}
  .btn.link{background:#fff;color:var(--brand-700);border-color:var(--outline)}
  .btn:active{transform:translateY(1px)}
  .result{border:1px dashed var(--outline);border-radius:12px;padding:14px;background:#fcfffe}
  .badge{display:inline-block;border-radius:999px;padding:2px 8px;font-size:.75rem;color:#fff}
  .pref{background:var(--pref)} .alt{background:var(--alt)} .second{background:var(--second)} .addon{background:var(--addon)} .ref{background:var(--ref)}
  .muted{color:var(--muted)}
  .list{display:grid;gap:10px}
  .row{border:1px solid var(--outline);border-radius:12px;padding:12px;background:#fff}
  .row h4{margin:.2rem 0}
  .chip{display:inline-block;margin:4px 6px 0 0;padding:4px 8px;border-radius:999px;background:#f0fffb;border:1px solid var(--outline);font-size:.8rem}
  .split{display:flex;gap:8px;flex-wrap:wrap}
  .warn{background:#fff7ed;border:1px solid #ffedd5}
  .searchbar{position:relative}
  .searchbar input{padding-left:40px}
  .magnify{position:absolute;left:10px;top:50%;transform:translateY(-50%);opacity:.6}
  .refbar{display:flex;gap:8px;flex-wrap:wrap;margin-top:10px}
  .refbar .btn{padding:8px 10px;font-size:.9rem}
  /* per-drug layout inside result */
  .drug{border:1px solid var(--outline);border-radius:10px;padding:10px;margin:8px 0;background:#fff}
  .drug .name{font-weight:700}
  /* combo/options layout */
  .combos{display:flex;flex-wrap:wrap;gap:10px;align-items:stretch}
  .option{flex:1;min-width:260px;border:1px solid var(--outline);background:#fff;border-radius:12px;padding:10px;box-shadow:var(--shadow)}
  .option h5{margin:.2rem 0 .25rem 0;font-size:.95rem;color:var(--muted)}
  .orDivider{align-self:center;font-weight:700;color:var(--muted);padding:6px 10px;border:1px dashed var(--outline);border-radius:999px;background:#f8fffd}