Managing Side Effects of Chemotherapy for Stomach Cancer

Going through chemotherapy for stomach cancer can feel like a rollercoaster—physically, emotionally, and mentally. While chemo plays a vital role in fighting the cancer cells, it can also come with side effects that turn everyday life upside down. The good news? You’re not alone, and many of these side effects can be managed with the right strategies. Let’s walk through the common issues and explore what you can do to feel more in control.


What to Expect from Chemotherapy for Stomach Cancer

So, what exactly happens when you begin chemotherapy? Typically, chemo drugs for stomach cancer—like 5-fluorouracil (5-FU), capecitabine, cisplatin, or oxaliplatin—are given through an IV or in pill form. Treatment is usually spread out over several weeks or months, often in cycles.

But no two people respond the same way. Some may breeze through with mild effects, while others face more intense symptoms. Understanding what’s coming helps you plan, ask the right questions, and feel more prepared.


Why Side Effects Happen During Chemotherapy

Ever wonder why chemo can cause so many issues? Here’s why: these drugs are powerful. They’re designed to kill fast-growing cancer cells—but they don’t always stop there. They can also affect other fast-growing cells in your body, like those in your gut, hair, or mouth. That’s what leads to side effects.

It’s not a sign of weakness or failure if you experience them—it’s a common part of the journey.


Nausea and Vomiting: How to Stay Ahead of It

This one hits hard for many patients. That wave of nausea after chemo can be relentless. But you don’t have to just endure it.

  • Take anti-nausea meds before you feel sick. Your doctor will likely prescribe drugs like ondansetron or metoclopramide. Don’t wait—take them early.
  • Eat small, bland meals. Crackers, toast, or plain rice can be gentle on the stomach.
  • Stay hydrated. Sip water or electrolyte drinks often.
  • Try ginger. Ginger tea or candies can naturally soothe your tummy.

If vomiting becomes frequent or uncontrollable, speak to your care team. They may adjust your meds or treatment schedule.


Fatigue and Weakness: Regaining Your Energy

Feel like you can barely lift your arms? Chemo-related fatigue is real—and frustrating.

  • Give yourself permission to rest. You’re not lazy—you’re healing.
  • Pace yourself. Break tasks into smaller steps.
  • Do light activities. Short walks or gentle stretching can sometimes boost energy, not drain it.
  • Ask for help. Let others cook, clean, or run errands.

Fatigue doesn’t always go away with sleep, so listen to your body. It’s okay to slow down.


Appetite Loss and Weight Changes

You might find yourself turned off by food—or notice you’re losing weight without trying. Chemo can alter your sense of taste or make eating a chore.

  • Try high-calorie, small meals. Think smoothies, full-fat yoghurts, or nut butters.
  • Don’t stress about eating ‘perfectly.’ The goal is to get calories in.
  • Experiment with flavours. What tastes bad today might be fine tomorrow.
  • Speak with a dietitian. They can offer tailored advice and meal plans.

Eating might feel like a task, but nourishing your body is part of healing.


Diarrhoea or Constipation: Finding the Balance

Your gut can become a battleground during chemo. Some people swing between diarrhoea and constipation.

  • For diarrhoea: Stick to low-fibre foods like white rice, bananas, or applesauce. Stay hydrated and ask about anti-diarrhoeal medications.
  • For constipation: Add gentle fibre (like oats), drink more water, and try warm drinks in the morning. Gentle movement also helps.

Don’t be shy—gut symptoms are incredibly common and nothing to feel embarrassed about.


Mouth Sores and Dry Mouth

Painful mouth sores can make even sipping water feel like fire. And dry mouth makes chewing or talking tough.

  • Use a soft-bristle toothbrush and mild mouthwash. Avoid anything with alcohol.
  • Rinse with baking soda and salt water. It soothes and keeps the area clean.
  • Avoid spicy, acidic, or crunchy foods. Go for soft, bland options.
  • Stay hydrated. Suck on ice chips or sugar-free candy if dry mouth kicks in.

These little adjustments can make a big difference in your comfort.


Hair Loss and Skin Changes

This one often hits emotionally more than physically. Losing hair—even temporarily—can affect your confidence.

  • Prepare ahead. Consider cutting hair short before it falls out.
  • Use gentle hair and skin products. Avoid harsh chemicals or heat.
  • Wear scarves, hats, or wigs if it helps. Or rock the bald look proudly.

Remember: your worth isn’t tied to your appearance. You’re strong—and beautiful—no matter what.


Low Blood Counts: How to Stay Safe

Chemo can lower your red cells (causing fatigue), white cells (raising infection risk), and platelets (causing bleeding).

  • Avoid crowded places. Or wear a mask when you go out.
  • Watch for signs of infection. Fever, chills, or sore throat? Don’t wait—call your doctor.
  • Eat iron-rich foods like spinach or fortified cereals if your red cells are low.
  • Report any unusual bruising or bleeding. This might signal low platelets.

Your medical team may suggest injections or transfusions to help—don’t hesitate to ask.


Chemo Brain: Dealing with Foggy Thinking

Ever walk into a room and forget why? Or struggle to find the right words? That’s chemo brain—and it’s more than just being tired.

  • Keep a notebook. Jot down reminders, appointments, and grocery lists.
  • Use phone alerts or sticky notes. Don’t rely on memory alone.
  • Do one thing at a time. Multitasking makes it worse.

This mental fog usually improves after treatment ends—but talk to your doctor if it interferes with daily life.


Emotional and Mental Health Support

Chemotherapy isn’t just hard on the body—it takes a toll on your spirit too. Feeling anxious, sad, or even numb is normal.

  • Join a support group. Sharing with others who “get it” can be healing.
  • Talk to a counsellor or psychologist. You don’t have to carry this alone.
  • Try mindfulness or journaling. It helps some people process emotions.

Your mental health is just as important as your physical recovery. Don’t ignore it.


When to Call Your Doctor

Not sure if a symptom is serious? Here’s a quick list of when to call:

  • Fever over 38°C (100.4°F)
  • Uncontrolled vomiting or diarrhoea
  • Trouble breathing
  • Bleeding that won’t stop
  • Sudden confusion or severe weakness

If something doesn’t feel right—trust your gut and reach out.


Integrative and Supportive Therapies

Can acupuncture help? Is massage safe? Many people find relief through complementary therapies, but always talk to your oncologist first.

  • Acupuncture may ease nausea or pain.
  • Massage therapy can reduce stress, but avoid deep tissue if your platelets are low.
  • Gentle yoga or tai chi can support strength and balance.

Even aromatherapy or music can uplift your mood. Explore what works for you.


Long-Term Side Effects to Watch For

Even after chemo ends, some side effects may linger—like fatigue, nerve pain (neuropathy), or fertility changes.

  • Keep follow-up appointments. Monitoring helps catch late effects early.
  • Report anything unusual. Your team needs to know.
  • Adopt healthy habits. Eat well, stay active, and rest.

Recovery is a journey, not a finish line.


Caregiver Tips: Supporting a Loved One Through Chemo

If you’re a caregiver, you might feel helpless at times. But your presence matters more than you think.

  • Listen without needing to fix. Sometimes, they just need to talk.
  • Help track symptoms and appointments. Two heads are better than one.
  • Take care of yourself too. You can’t pour from an empty cup.

Your support helps your loved one heal—emotionally and physically.


Final Thoughts

Managing the side effects of chemotherapy for stomach cancer isn’t easy—but it is doable. With the right strategies, a good support system, and open communication with your medical team, you can navigate this tough chapter and come out stronger on the other side.


References

  1. “Chemotherapy Side Effects”, American Cancer Society, 2022. https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/chemotherapy/chemotherapy-side-effects.html
  2. “Coping with Chemotherapy”, Cancer Research UK, 2023. https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/chemotherapy/coping
  3. “Managing Cancer-related Side Effects”, National Cancer Institute, 2024. https://www.cancer.gov/about-cancer/treatment/side-effects
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